Summary

Defrosted will leave readers questioning the fine line between right and wrong.

4.5-STAR REVIEW: DEFROSTED by Cristina LePort

The Description

Publication Date: June 2, 2026

A Frightening Vision of the Future, And an Electrifying New Thriller, from the Acclaimed Author of Dissection and Change of Heart

Dr. Cristina LePort raises the bar with Defrosted, a captivating fusion of science, medicine, and political intrigue that redefines the boundaries of the thriller genre.

Two centuries into the future, cryogenically preserved scientist Dr. Peter Royce and his wife, Monica, awaken to a dystopian world where human worth is dictated by productivity and freedom is a distant memory. A devastating biological entity, known as mitocancer, looms as a global threat, and Peter must uncover the truth of his past to save humanity’s future.

From the icy wilderness of Alaska to the corridors of power in a reimagined Washington, D.C., Defrosted explores the clash of high-tech medical breakthroughs and ethical dilemmas. As power plays escalate and secrets unravel, Peter, Monica, and a cast of vividly drawn characters are thrust into a battle for survival that questions the very essence of humanity.

As Midwest Book Review notes, “This medical & political thriller pairs science, medicine, and cat-and-mouse games… Readers drawn by either the thriller promise or the medical backdrop will find that Defrosted’s ability to thaw out the truth of purposes, visions, and the consequences of actions yet to be tested on moral and ethical grounds gives much food for thought.”

Perfect for book clubs engaged in debates on medical ethics and cutting-edge technology, Defrosted challenges readers to question where progress ends and humanity begins. A standalone triumph, it cements LePort’s reputation as a master storyteller and a thought leader in speculative and medical fiction.

The Review

Two hundred years in the future, a deadly entity threatens to destroy humanity while the only solution lies frozen in the past.

Author Cristina LePort leverages her medical background for inspiration in Defrosted , a dystopian thriller that combines scientific, medical, and political twists.

Think of an invincible army of mitochondria acting as a cohesive colony, resistant to any efforts to wipe it out. Instead, it mutates and continues to grow. It spreads along the ground, gaining strength and multiplying with every bit of fuel.

Bureaucracy is at its finest in the future world, with a pompous medical director reluctantly agreeing to thaw out the only person with any documented knowledge of what is referred to as Mitocancer.

Dr. Peter Royce and his wife, Monica, emerge from their cryogenically frozen state only to be thrust into chaos. Ethical dilemmas shadow every decision courtesy of a society that values life based on utility.

Defrosted will leave readers questioning the fine line between right and wrong.Buy Links

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About The Author

Dr. Cristina LePort was born in Bologna, Italy. She attended medical school at the University of Bologna and then completed her medical training at Long Island College Hospital in Brooklyn and at the University of California, Los Angeles. She is board certified in Internal Medicine and Cardiovascular Diseases and has been practicing medicine for more than thirty years. Cristina is also the Chief Medical Officer and co-founder of Genescient, a biotech company devoted to genetic research on aging and the amelioration of chronic diseases. Medicine and fiction are her twin passions, and she is absolutely thrilled to be able to share her medical thrillers with the world.

Cristina LePort currently resides in Orange County, California, with her husband Peter LePort, a general surgeon. They have three children and three grandchildren.

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REVIEW AUTHOR

Amy Wilson
Amy Wilson
My name is Amy W., and I am a book addict. I will never forget the day I came home from junior high school to find my mom waiting for me with one of the Harlequin novels from my stash. As she was gearing up for the "you shouldn't be reading this" lecture, I told her the characters get married in the end. I'm just glad she didn't find the Bertrice Small book hidden in my closet. I have diverse reading tastes, evident by the wide array of genres on my Kindle. As I made the transition to an e-reader, I found myself worrying that something could happen to it. As a result, I am now the proud owner of four Kindles -- all different kinds, but plenty of back-ups! "Fifty Shades of Grey" gets high marks on my favorites list -- not for character development or dialogue (definitely not!), but because it blazed new ground for those of us who believe provocative fiction is more than just an explicit cover. Sylvia Day, Lexie Blake, and Kristin Hannah are some of my favorite authors. Speaking of diverse tastes, I also enjoy Dean Koontz, Iris Johansen, and J.A. Konrath. I’m always ready to discover new-to-me authors, especially when I toss in a palate cleanser that is much different than what I would normally read. Give me something with a well-defined storyline, add some suspense (or spice), and I am a happy reader. Give me a happily ever after, and I am downright giddy.

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Defrosted will leave readers questioning the fine line between right and wrong.4.5-STAR REVIEW: DEFROSTED by Cristina LePort